preclinical

adjective

pre·​clin·​i·​cal (ˌ)prē-ˈkli-ni-kəl How to pronounce preclinical (audio)
1
: of, relating to, or concerned with the period preceding clinical manifestations
2
: of, relating to, or being the period in medical or dental education preceding the clinical study of medicine or dentistry
3
: occurring prior to clinical testing
a preclinical animal study of a new therapy

Examples of preclinical in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Cesar de la Fuente-Nunez is a presidential associate professor at the University of Pennsylvania who has pioneered artificial intelligence and experimental approaches that have greatly accelerated antibiotic discovery, yielding numerous preclinical candidates. Henry Skinner, STAT, 5 Mar. 2026 There are also openings on its preclinical team. Andrea Guzmán, Austin American Statesman, 27 Feb. 2026 But those preclinical studies uncovered how T cells, specialized white blood cells that are programmed to recognize and exterminate threats like cancer, are more active in the morning. Brenda Goodman, CNN Money, 6 Feb. 2026 In preclinical studies, ER-100 was delivered directly into the eye through intravitreal injection. Neetika Walter, Interesting Engineering, 4 Feb. 2026 See All Example Sentences for preclinical

Word History

First Known Use

1876, in the meaning defined at sense 1

Time Traveler
The first known use of preclinical was in 1876

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Cite this Entry

“Preclinical.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/preclinical. Accessed 27 Mar. 2026.

Medical Definition

preclinical

adjective
pre·​clin·​i·​cal (ˈ)prē-ˈklin-i-kəl How to pronounce preclinical (audio)
1
a
: of, relating to, concerned with, or being the period preceding clinical manifestations
the preclinical stage of diabetes mellitus
b
: occurring prior to a clinical trial
preclinical animal testing to assess a drug's safety
2
: of, relating to, or being the period in medical or dental education preceding the clinical study of medicine or dentistry
the preclinical years
specifically : of or relating to the early period of prescribed medical or dental study devoted to the basic sciences (as anatomy, physiology, and pathology)
preclinical studies
3
: of, relating to, or being a science basic to medicine
research in the preclinical sciences
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